STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itkTyrosine-protein kinase. (617 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
0.666
LOC101468207
B cell linker.
   
 0.659
cd247
Uncharacterized protein.
   
 0.654
LOC101470260
RUN and FYVE domain containing 1.
    
  0.613
syk
Tyrosine-protein kinase.
  
0.606
LOC101466346
Tyrosine-protein kinase.
  
0.604
mst1r
Macrophage stimulating 1 receptor b.
    
0.598
met
MET proto-oncogene, receptor tyrosine kinase.
    
0.598
LOC101469724
Macrophage stimulating 1 receptor a.
    
0.598
LOC101487152
GRB2 related adaptor protein 2b.
   
 0.579
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.