STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101472021Renin; Belongs to the peptidase A1 family. (396 aa)    
Predicted Functional Partners:
agt
Angiotensinogen; Belongs to the serpin family.
   
 0.722
atp6ap2
ATPase H+ transporting accessory protein 2.
   
 0.549
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.506
LOC101469513
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 0.468
ENSMZEP00005033081
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 0.468
LOC101469506
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.453
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 0.435
ace
Angiotensin-converting enzyme.
      
 0.432
ctso
Cathepsin O; Belongs to the peptidase C1 family.
   
 0.421
LOC101484741
Lysosomal associated membrane protein 1a.
   
 
 0.402
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.