STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TVD_02720Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (71 aa)    
Predicted Functional Partners:
TVD_00725
Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.566
TVD_02715
Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.542
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
   
  
 0.537
acsA
3-hydroxypropionyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.524
TVD_04090
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.444
TVD_02710
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.409
Your Current Organism:
Thioalkalivibrio versutus
NCBI taxonomy Id: 106634
Other names: CBS 100464, DSM 13738, T. versutus, Thialkalivibrio versutus, Thioalkalivibrio versutus Sorokin et al. 2001, strain AL 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.