STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B2SH2B adaptor protein 2. (602 aa)    
Predicted Functional Partners:
INSR
Insulin receptor.
    
 0.918
GRB2
Growth factor receptor bound protein 2.
    
 0.901
INSRR
Insulin receptor related receptor.
    
 0.892
IGF1R
Insulin like growth factor 1 receptor.
    
 0.892
NTRK3
Neurotrophic receptor tyrosine kinase 3.
    
 0.866
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.856
NTRK1
Neurotrophic receptor tyrosine kinase 1.
    
 0.855
JAK2
Janus kinase 2.
    
 0.827
JAK3
Janus kinase 3.
    
 0.827
SH2B3
SH2B adaptor protein 3.
    
 
0.826
Your Current Organism:
Chelonoidis abingdonii
NCBI taxonomy Id: 106734
Other names: Abingdon island giant tortoise, C. abingdonii, Chelonoidis nigra abingdonii, Geochelone nigra abigdonii, Geochelone nigra abingdoni, Geochelone nigra ephippium
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.