STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM8A1Family with sequence similarity 8 member A1. (184 aa)    
Predicted Functional Partners:
SYVN1
Synoviolin 1.
    
 0.969
AMFR
Autocrine motility factor receptor.
    
 0.969
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 0.965
SEL1L2
SEL1L2 adaptor subunit of ERAD E3 ligase.
    
 0.919
SEL1L3
SEL1L family member 3.
    
 0.876
RNF145
Ring finger protein 145.
    
 0.874
ENSCABP00000012882
annotation not available
    
 0.874
RNF139
Ring finger protein 139.
    
 0.868
CHFR
Checkpoint with forkhead and ring finger domains.
    
  0.863
DERL1
Derlin 1.
   
 
 0.859
Your Current Organism:
Chelonoidis abingdonii
NCBI taxonomy Id: 106734
Other names: Abingdon island giant tortoise, C. abingdonii, Chelonoidis nigra abingdonii, Geochelone nigra abigdonii, Geochelone nigra abingdoni, Geochelone nigra ephippium
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.