STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROS1ROS proto-oncogene 1, receptor tyrosine kinase. (2216 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.904
GAB2
GRB2 associated binding protein 2.
    
 0.848
PTN
Pleiotrophin.
    
 0.789
ENSCABP00000014338
annotation not available
   
 0.762
GAB1
GRB2 associated binding protein 1.
    
 0.738
ENSCABP00000005133
annotation not available
    
 0.735
TNS2
Tensin 2.
    
 0.735
TNS1
Tensin 1.
    
 0.735
CBL
Cbl proto-oncogene.
    
 0.734
ENSCABP00000014959
annotation not available
    
 0.734
Your Current Organism:
Chelonoidis abingdonii
NCBI taxonomy Id: 106734
Other names: Abingdon island giant tortoise, C. abingdonii, Chelonoidis nigra abingdonii, Geochelone nigra abigdonii, Geochelone nigra abingdoni, Geochelone nigra ephippium
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.