STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (573 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr.
 
 0.999
LRC_00800
PTS system, fructose specific IIABC component.
 
  
 0.995
LRC_18780
PTS system, sucrose-specific IIABC component.
 
 0.983
LRC_18820
PTS system, glucose-specific IIABC component.
 
 0.982
LRC_18250
GPH family glycoside-pentoside-hexuronide:cation symporter.
 
 0.842
lacE
Cellobiose PTS, EIIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
     
 0.818
pfkB
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.803
LRC_06960
Conserved hypothetical protein.
       0.639
LRC_18870
PTS system, mannose-specific IIAB component.
  
  
 0.637
LRC_06990
Glycosyltransferase.
       0.608
Your Current Organism:
Lactobacillus ruminis
NCBI taxonomy Id: 1069534
Other names: L. ruminis ATCC 27782, Lactobacillus ruminis ATCC 27782, Lactobacillus ruminis str. ATCC 27782, Lactobacillus ruminis strain ATCC 27782
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