STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRC_09030Diphosphomevalonate decarboxylase. (319 aa)    
Predicted Functional Partners:
LRC_09020
Phosphomevalonate kinase.
 
 
 0.998
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.994
LRC_09040
Mevalonate kinase.
 
  
 0.994
LRC_08340
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.949
mvaS
Hydroxymethylglutaryl-CoA synthase.
 
 
 0.926
LRC_04410
3-hydroxy-3-methylglutaryl-coenzyme A reductase/3-hydroxy-3-methylglutaryl-coenzyme Auctase; Belongs to the HMG-CoA reductase family.
 
  
 0.885
dinG
ATP-dependent helicase, DinG family; 3'-5' exonuclease.
       0.725
lysS
Lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
      0.665
LRC_09060
Conserved hypothetical secreted protein.
       0.633
asnS
asparaginyl-tRNA synthetase.
  
    0.585
Your Current Organism:
Lactobacillus ruminis
NCBI taxonomy Id: 1069534
Other names: L. ruminis ATCC 27782, Lactobacillus ruminis ATCC 27782, Lactobacillus ruminis str. ATCC 27782, Lactobacillus ruminis strain ATCC 27782
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.