node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PNEG_00490 | PNEG_00705 | M7PC53 | M7NQW0 | Fumarate hydratase, mitochondrial. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.967 |
PNEG_00490 | PNEG_01968 | M7PC53 | M7P7G5 | Fumarate hydratase, mitochondrial. | Aminotran_1_2 domain-containing protein. | 0.909 |
PNEG_00490 | PNEG_02302 | M7PC53 | M7NL19 | Fumarate hydratase, mitochondrial. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.667 |
PNEG_00490 | PNEG_02570 | M7PC53 | M7P5V4 | Fumarate hydratase, mitochondrial. | Citrate synthase; Belongs to the citrate synthase family. | 0.946 |
PNEG_00490 | PNEG_02625 | M7PC53 | M7NJQ3 | Fumarate hydratase, mitochondrial. | Malate dehydrogenase. | 0.986 |
PNEG_00490 | PNEG_02661 | M7PC53 | M7NP45 | Fumarate hydratase, mitochondrial. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.770 |
PNEG_00490 | PNEG_02733 | M7PC53 | M7PER1 | Fumarate hydratase, mitochondrial. | Uncharacterized protein. | 0.762 |
PNEG_00490 | PNEG_02734 | M7PC53 | M7P522 | Fumarate hydratase, mitochondrial. | ATP-citrate synthase subunit 1. | 0.762 |
PNEG_00490 | PNEG_03044 | M7PC53 | M7NMW1 | Fumarate hydratase, mitochondrial. | Aspartate aminotransferase. | 0.925 |
PNEG_00705 | PNEG_00490 | M7NQW0 | M7PC53 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Fumarate hydratase, mitochondrial. | 0.967 |
PNEG_00705 | PNEG_02302 | M7NQW0 | M7NL19 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.682 |
PNEG_00705 | PNEG_02570 | M7NQW0 | M7P5V4 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Citrate synthase; Belongs to the citrate synthase family. | 0.976 |
PNEG_00705 | PNEG_02625 | M7NQW0 | M7NJQ3 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Malate dehydrogenase. | 0.960 |
PNEG_00705 | PNEG_02661 | M7NQW0 | M7NP45 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.884 |
PNEG_00705 | PNEG_02733 | M7NQW0 | M7PER1 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Uncharacterized protein. | 0.999 |
PNEG_00705 | PNEG_02734 | M7NQW0 | M7P522 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | ATP-citrate synthase subunit 1. | 0.993 |
PNEG_01968 | PNEG_00490 | M7P7G5 | M7PC53 | Aminotran_1_2 domain-containing protein. | Fumarate hydratase, mitochondrial. | 0.909 |
PNEG_01968 | PNEG_02300 | M7P7G5 | M7NQH7 | Aminotran_1_2 domain-containing protein. | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.481 |
PNEG_01968 | PNEG_02302 | M7P7G5 | M7NL19 | Aminotran_1_2 domain-containing protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.477 |
PNEG_01968 | PNEG_02570 | M7P7G5 | M7P5V4 | Aminotran_1_2 domain-containing protein. | Citrate synthase; Belongs to the citrate synthase family. | 0.891 |