STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_02625Malate dehydrogenase. (340 aa)    
Predicted Functional Partners:
PNEG_02570
Citrate synthase; Belongs to the citrate synthase family.
  
 0.994
PNEG_00490
Fumarate hydratase, mitochondrial.
  
 0.986
PNEG_03044
Aspartate aminotransferase.
   
 0.978
PNEG_01968
Aminotran_1_2 domain-containing protein.
   
 0.963
PNEG_00705
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.960
PNEG_02302
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.958
PNEG_02661
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.955
PNEG_02734
ATP-citrate synthase subunit 1.
  
 0.953
PNEG_02733
Uncharacterized protein.
  
 0.953
PNEG_02300
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
  
 
 0.941
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
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