STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_02558HECT domain-containing protein. (1653 aa)    
Predicted Functional Partners:
PNEG_00259
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.869
PNEG_01417
U-box domain-containing protein.
   
 0.847
PNEG_02945
UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.
   
 0.735
PNEG_03006
HECT domain-containing protein.
   
 
0.725
PNEG_01699
Polyubiquitin.
   
 0.696
PNEG_02771
C2H2-type domain-containing protein.
    
 0.691
PNEG_02326
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.691
PNEG_00387
E2_bind domain-containing protein.
    
 0.689
PNEG_03270
Ubiquitin-conjugating enzyme E2-16 kDa; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.684
PNEG_00456
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.684
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
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