STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_01064Polyketide_cyc domain-containing protein. (192 aa)    
Predicted Functional Partners:
PNEG_01605
Hydroxyacylglutathione hydrolase.
    
 0.790
PNEG_00216
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
 0.744
PNEG_02515
NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
      
 0.699
PNEG_03232
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 0.667
PNEG_01348
ABC1 domain-containing protein.
    
 
 0.666
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
    
 0.639
PNEG_03611
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
   
 
 0.571
PNEG_04328
Aldo_ket_red domain-containing protein.
    
  0.559
PNEG_03308
Uncharacterized protein.
    
  0.559
COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
    
 
 0.517
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.