node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PNEG_00379 | PNEG_00635 | M7PBV0 | M7NQN5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.996 |
PNEG_00379 | PNEG_01054 | M7PBV0 | M7NQB5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. | 0.701 |
PNEG_00379 | PNEG_02095 | M7PBV0 | M7NQG2 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ubiquitin-like protein pmt3/smt3. | 0.874 |
PNEG_00379 | PNEG_02158 | M7PBV0 | M7NQN1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family. | 0.860 |
PNEG_00379 | PNEG_02771 | M7PBV0 | M7P548 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | C2H2-type domain-containing protein. | 0.701 |
PNEG_00379 | PNEG_03275 | M7PBV0 | M7PDB0 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | SMC_N domain-containing protein. | 0.593 |
PNEG_00635 | PNEG_00379 | M7NQN5 | M7PBV0 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.996 |
PNEG_00635 | PNEG_01054 | M7NQN5 | M7NQB5 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. | 0.910 |
PNEG_00635 | PNEG_01962 | M7NQN5 | M7NM98 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Structural maintenance of chromosomes protein. | 0.962 |
PNEG_00635 | PNEG_02095 | M7NQN5 | M7NQG2 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Ubiquitin-like protein pmt3/smt3. | 0.911 |
PNEG_00635 | PNEG_02158 | M7NQN5 | M7NQN1 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family. | 0.854 |
PNEG_00635 | PNEG_02646 | M7NQN5 | M7P4V2 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. | 0.848 |
PNEG_00635 | PNEG_02771 | M7NQN5 | M7P548 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | C2H2-type domain-containing protein. | 0.945 |
PNEG_00635 | PNEG_03058 | M7NQN5 | M7NMX5 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Structural maintenance of chromosomes protein. | 0.913 |
PNEG_00635 | PNEG_03217 | M7NQN5 | M7NMD6 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Uncharacterized protein. | 0.860 |
PNEG_00635 | PNEG_03275 | M7NQN5 | M7PDB0 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | SMC_N domain-containing protein. | 0.876 |
PNEG_01054 | PNEG_00379 | M7NQB5 | M7PBV0 | Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.701 |
PNEG_01054 | PNEG_00635 | M7NQB5 | M7NQN5 | Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.910 |
PNEG_01054 | PNEG_01962 | M7NQB5 | M7NM98 | Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. | Structural maintenance of chromosomes protein. | 0.678 |
PNEG_01054 | PNEG_02095 | M7NQB5 | M7NQG2 | Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-like protein pmt3/smt3. | 0.853 |