STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_01946Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (735 aa)    
Predicted Functional Partners:
PNEG_02056
Cell division control protein 48; Belongs to the AAA ATPase family.
   
 0.999
PNEG_01867
Uncharacterized protein.
    
 0.982
PNEG_02243
Clr2_transil domain-containing protein.
    
 
 0.971
PNEG_02256
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
  
 0.970
PNEG_03448
Deacetylase sirtuin-type domain-containing protein.
   
 
 0.951
PNEG_00674
Histone H3; Belongs to the histone H3 family.
   
 0.918
PNEG_03485
Protein GZF3.
    
 0.887
PNEG_03286
Histone H2A; Belongs to the histone H2A family.
    
 0.884
PNEG_01529
WD_REPEATS_REGION domain-containing protein.
   
 0.882
PNEG_00381
HDAC_interact domain-containing protein.
    
 0.862
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.