STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_00288Thioredoxin; Belongs to the thioredoxin family. (103 aa)    
Predicted Functional Partners:
PNEG_03256
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.967
PNEG_04344
Arrestin_C domain-containing protein.
    
 0.965
PNEG_02158
SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.944
PNEG_00130
Thioredoxin reductase.
    
 
 0.933
PNEG_01571
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.919
PNEG_03167
Dihydrolipoyl dehydrogenase.
  
 0.859
PNEG_00023
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.857
PNEG_03075
Uncharacterized protein.
   
 
 0.834
PNEG_02300
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
  
 0.830
PNEG_03325
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.826
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
Server load: low (18%) [HD]