STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_00452ATP-dependent RNA helicase eIF4A; Belongs to the DEAD box helicase family. (400 aa)    
Predicted Functional Partners:
PNEG_04281
MIF4G domain-containing protein.
   
 0.999
PNEG_01768
W2 domain-containing protein.
   
 0.991
PNEG_03075
Uncharacterized protein.
  
 
 0.991
TIF34
Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 
 0.984
PNEG_01622
RRM domain-containing protein.
 
 
 0.980
PNEG_03177
Elongation factor 3.
  
 
 0.978
PNEG_03112
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
   
 0.978
PNEG_03000
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
 
 
 0.971
PNEG_01269
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.971
PNEG_01751
Uncharacterized protein.
   
 0.968
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.