STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_00153Uncharacterized protein. (332 aa)    
Predicted Functional Partners:
PNEG_02095
Ubiquitin-like protein pmt3/smt3.
    
 
 0.755
PNEG_01143
PLD phosphodiesterase domain-containing protein.
    
 
 0.729
PNEG_00379
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.619
PNEG_02385
Uncharacterized protein.
    
 
 0.599
PNEG_02642
3'-5' exonuclease domain-containing protein.
    
 
 0.560
PNEG_00329
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 
 0.554
PNEG_01523
ULP_PROTEASE domain-containing protein.
    
 
 0.517
PNEG_00324
ULP_PROTEASE domain-containing protein.
    
 
 0.507
PNEG_02056
Cell division control protein 48; Belongs to the AAA ATPase family.
    
 
 0.437
PNEG_01329
Uncharacterized protein.
    
 
 0.423
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.