STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macBMacrolide export ATP-binding/permease protein macB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (702 aa)    
Predicted Functional Partners:
macA
Macrolide efflux protein MacA; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type t:transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.999
CCD28847.1
RND efflux system, outer membrane lipoprotein,NodT family precursor; Evidence 2b:Function of strongly homologous gene; Product type t:transporter.
 
 0.999
acrA
Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type t:transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.999
oprM
Outer membrane efflux protein OprB; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type t:transporter.
 
 0.999
lolC
Lipoprotein-releasing system transmembrane protein LolC; Evidence 2b:Function of strongly homologous gene; Product type t:transporter.
 
 0.997
lolD
Lipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
 
0.963
lolA
Fragment of putative DNA translocase ftsK (part 2); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.941
CCD28820.1
Putative non-ribosomal peptide synthase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pcp:putative cell process.
 
  
 0.889
CCD28819.1
Putative Non-ribosomal peptide synthase,PvdD/PvdJ-like; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme.
 
  
 0.883
CCD30067.1
Sensor protein; Evidence 2b:Function of strongly homologous gene; Product type e:enzyme.
  
 
 0.879
Your Current Organism:
Glomeribacter gigasporarum
NCBI taxonomy Id: 1070319
Other names: C. Glomeribacter gigasporarum BEG34, Candidatus Glomeribacter gigasporarum BEG34, Candidatus Glomeribacter gigasporarum str. BEG34, Candidatus Glomeribacter gigasporarum strain BEG34
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