STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hdaATPase regulatory factor involved in DnaA inactivation; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f:factor; Belongs to the DnaA family. (244 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.980
CCD28820.1
Putative non-ribosomal peptide synthase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pcp:putative cell process.
     
 0.875
CCD28819.1
Putative Non-ribosomal peptide synthase,PvdD/PvdJ-like; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme.
     
 0.870
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
    
 
 0.780
CCD29508.1
Putative N-6 DNA methylase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme.
       0.773
parA
Partitioning protein parA; Evidence 2b:Function of strongly homologous gene; Product type e:enzyme.
  
 
 0.765
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
 
0.703
pcnB
Poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
     0.700
folK
2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme.
       0.660
CCD30230.1
Putative Histidine kinase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme.
     
 0.653
Your Current Organism:
Glomeribacter gigasporarum
NCBI taxonomy Id: 1070319
Other names: C. Glomeribacter gigasporarum BEG34, Candidatus Glomeribacter gigasporarum BEG34, Candidatus Glomeribacter gigasporarum str. BEG34, Candidatus Glomeribacter gigasporarum strain BEG34
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