Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | glyA | CAGGBEG34_190026 | CAGGBEG34_280052 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.647 |
| carB | guaA | CAGGBEG34_190026 | CAGGBEG34_180086 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | 0.839 |
| carB | guaB | CAGGBEG34_190026 | CAGGBEG34_180088 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.807 |
| carB | purA | CAGGBEG34_190026 | CAGGBEG34_560003 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.836 |
| carB | purB | CAGGBEG34_190026 | CAGGBEG34_290001 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Putative adenylosuccinate lyase (fragment); Evidence 2b:Function of strongly homologous gene; Product type e:enzyme. | 0.590 |
| carB | purC | CAGGBEG34_190026 | CAGGBEG34_680003 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Elongation factor P (EF-P) (fragment); Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f:factor; Belongs to the SAICAR synthetase family. | 0.416 |
| carB | purF | CAGGBEG34_190026 | CAGGBEG34_180113 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.869 |
| carB | purH | CAGGBEG34_190026 | CAGGBEG34_280046 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme. | 0.675 |
| carB | purL | CAGGBEG34_190026 | CAGGBEG34_260001 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme. | 0.947 |
| carB | pyrD | CAGGBEG34_190026 | CAGGBEG34_210032 | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | Dihydroorotate dehydrogenase (Dihydroorotate oxidase) (DHOdehase) (DHODase) (DHOD); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.982 |
| glyA | carB | CAGGBEG34_280052 | CAGGBEG34_190026 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | 0.647 |
| glyA | guaA | CAGGBEG34_280052 | CAGGBEG34_180086 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | 0.893 |
| glyA | guaB | CAGGBEG34_280052 | CAGGBEG34_180088 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.709 |
| glyA | purA | CAGGBEG34_280052 | CAGGBEG34_560003 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.783 |
| glyA | purB | CAGGBEG34_280052 | CAGGBEG34_290001 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative adenylosuccinate lyase (fragment); Evidence 2b:Function of strongly homologous gene; Product type e:enzyme. | 0.803 |
| glyA | purC | CAGGBEG34_280052 | CAGGBEG34_680003 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Elongation factor P (EF-P) (fragment); Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f:factor; Belongs to the SAICAR synthetase family. | 0.669 |
| glyA | purF | CAGGBEG34_280052 | CAGGBEG34_180113 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.764 |
| glyA | purH | CAGGBEG34_280052 | CAGGBEG34_280046 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme. | 0.961 |
| glyA | purL | CAGGBEG34_280052 | CAGGBEG34_260001 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme. | 0.992 |
| guaA | carB | CAGGBEG34_180086 | CAGGBEG34_190026 | GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | Carbamoyl phosphate synthase, large subunit; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the CarB family. | 0.839 |
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