A0A1L9S714 protein (Penicilliopsis zonata) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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[Homology]

Score

A0A1L9S714

Uncharacterized protein. (347 aa)

Predicted Functional Partners:

A0A1L9S705

0.948

A0A1L9S700

0.830

A0A1L9SQX3

0.720

A0A1L9S7Y9

0.697

A0A1L9SMQ0

0.648

A0A1L9SH60

0.639

A0A1L9SHI3

0.637

A0A1L9SWA3

0.629

A0A1L9S6P9

0.624

A0A1L9SVU3

0.610

Your Current Organism:

Penicilliopsis zonata

NCBI taxonomy Id: 1073090
Other names: Aspergillus zonatus CBS 506.65, P. zonata CBS 506.65, Penicilliopsis zonata CBS 506.65

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1L9S6P9	A0A1L9S714	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.624
A0A1L9S6P9	A0A1L9SHI3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	MaoC-like domain-containing protein.	0.545
A0A1L9S6P9	A0A1L9SVU3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	RING-type domain-containing protein.	0.943
A0A1L9S6P9	A0A1L9SWA3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Pex14_N domain-containing protein.	0.848
A0A1L9S700	A0A1L9S705	Uncharacterized protein.	MR_MLE domain-containing protein.	0.836
A0A1L9S700	A0A1L9S714	Uncharacterized protein.	Uncharacterized protein.	0.830
A0A1L9S705	A0A1L9S700	MR_MLE domain-containing protein.	Uncharacterized protein.	0.836
A0A1L9S705	A0A1L9S714	MR_MLE domain-containing protein.	Uncharacterized protein.	0.948
A0A1L9S705	A0A1L9S7Y9	MR_MLE domain-containing protein.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.723
A0A1L9S705	A0A1L9SH60	MR_MLE domain-containing protein.	PKS_KS domain-containing protein.	0.656
A0A1L9S705	A0A1L9SHI3	MR_MLE domain-containing protein.	MaoC-like domain-containing protein.	0.470
A0A1L9S705	A0A1L9SMQ0	MR_MLE domain-containing protein.	2Fe-2S ferredoxin-type domain-containing protein.	0.646
A0A1L9S705	A0A1L9SQX3	MR_MLE domain-containing protein.	PKS_AT domain-containing protein.	0.743
A0A1L9S714	A0A1L9S6P9	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.624
A0A1L9S714	A0A1L9S700	Uncharacterized protein.	Uncharacterized protein.	0.830
A0A1L9S714	A0A1L9S705	Uncharacterized protein.	MR_MLE domain-containing protein.	0.948
A0A1L9S714	A0A1L9S7Y9	Uncharacterized protein.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.697
A0A1L9S714	A0A1L9SH60	Uncharacterized protein.	PKS_KS domain-containing protein.	0.639
A0A1L9S714	A0A1L9SHI3	Uncharacterized protein.	MaoC-like domain-containing protein.	0.637
A0A1L9S714	A0A1L9SMQ0	Uncharacterized protein.	2Fe-2S ferredoxin-type domain-containing protein.	0.648

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.933

expected number of edges:

18

PPI enrichment p-value:

6.73e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009116

Nucleoside metabolic process

3 of 10

2.01

1.31

0.0029

GO:0002100

tRNA wobble adenosine to inosine editing

2 of 2

2.54

1.1

0.0098

GO:0043094

Cellular metabolic compound salvage

2 of 6

2.06

0.89

0.0209

GO:0008295

Spermidine biosynthetic process

2 of 6

2.06

0.89

0.0209

GO:0055086

Nucleobase-containing small molecule metabolic process

4 of 117

1.07

0.64

0.0209

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019239

Deaminase activity

3 of 5

2.31

1.71

0.00059

GO:0016814

Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

3 of 8

2.11

1.58

0.00087

GO:0052717

tRNA-specific adenosine-34 deaminase activity

2 of 2

2.54

1.19

0.0067

GO:0016810

Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

4 of 53

1.41

1.08

0.0027

GO:0004766

Spermidine synthase activity

2 of 5

2.14

1.0

0.0134

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1418

Mixed, incl. Nucleoside metabolic process, and Deaminase activity

7 of 10

2.38

5.62

2.13e-12

CL:1421

Nucleoside metabolic process, and Deaminase activity

4 of 5

2.44

3.2

7.13e-07

CL:1154

Cellular amino acid biosynthetic process, and Ribonucleoside monophosphate biosynthetic process

9 of 142

1.34

2.08

2.86e-09

CL:1328

Polyamine metabolic process

2 of 6

2.06

0.84

0.0262

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00330

Arginine and proline metabolism

3 of 25

1.61

1.16

0.0032

map00270

Cysteine and methionine metabolism

3 of 33

1.49

1.05

0.0046

map00480

Glutathione metabolism

2 of 16

1.63

0.75

0.0318

map00230

Purine metabolism

3 of 82

1.1

0.59

0.0351

map01100

Metabolic pathways

11 of 1094

0.54

0.46

0.00014

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0378

Hydrolase

6 of 247

0.92

0.67

0.0057

KW-0862

Zinc

3 of 52

1.3

0.62

0.0430

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