STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1L9SC95Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (416 aa)    
Predicted Functional Partners:
A0A1L9SHU6
Pterin-binding domain-containing protein.
 
 
 0.996
A0A1L9SI20
Thymidylat_synt domain-containing protein.
     
 0.927
A0A1L9STN4
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.902
A0A1L9SBR9
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
  
  
0.897
A0A1L9SN20
Uncharacterized protein.
  
 
 0.877
A0A1L9SBB8
DUF218 domain-containing protein.
 
      0.871
A0A1L9SFZ7
Uncharacterized protein.
    
 0.868
A0A1L9SW95
FolB domain-containing protein.
  
 
 0.865
A0A1L9S8G5
FSH1 domain-containing protein.
     
 0.828
A0A1L9SCW7
FSH1 domain-containing protein.
     
 0.828
Your Current Organism:
Penicilliopsis zonata
NCBI taxonomy Id: 1073090
Other names: Aspergillus zonatus CBS 506.65, P. zonata CBS 506.65, Penicilliopsis zonata CBS 506.65
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