node1 | node2 | node1 annotation | node2 annotation | score |
A0A1L9SBR9 | A0A1L9SC95 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.897 |
A0A1L9SBR9 | A0A1L9SI20 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylat_synt domain-containing protein. | 0.931 |
A0A1L9SBR9 | A0A1L9SJY2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Formyl_trans_N domain-containing protein. | 0.419 |
A0A1L9SBR9 | A0A1L9SN20 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Uncharacterized protein. | 0.892 |
A0A1L9SBR9 | A0A1L9SRF2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.579 |
A0A1L9SBR9 | A0A1L9STM9 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.806 |
A0A1L9SBR9 | A0A1L9STN4 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.902 |
A0A1L9SBR9 | A0A1L9SW33 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.806 |
A0A1L9SBZ0 | A0A1L9SHW8 | MGS domain-containing protein. | Formyl_trans_N domain-containing protein. | 0.988 |
A0A1L9SBZ0 | A0A1L9SI20 | MGS domain-containing protein. | Thymidylat_synt domain-containing protein. | 0.854 |
A0A1L9SBZ0 | A0A1L9SJY2 | MGS domain-containing protein. | Formyl_trans_N domain-containing protein. | 0.790 |
A0A1L9SBZ0 | A0A1L9SN20 | MGS domain-containing protein. | Uncharacterized protein. | 0.989 |
A0A1L9SBZ0 | A0A1L9SRF2 | MGS domain-containing protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.948 |
A0A1L9SBZ0 | A0A1L9STM9 | MGS domain-containing protein. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.983 |
A0A1L9SBZ0 | A0A1L9STN4 | MGS domain-containing protein. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.908 |
A0A1L9SBZ0 | A0A1L9SW33 | MGS domain-containing protein. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.983 |
A0A1L9SC95 | A0A1L9SBR9 | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.897 |
A0A1L9SC95 | A0A1L9SI20 | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | Thymidylat_synt domain-containing protein. | 0.927 |
A0A1L9SC95 | A0A1L9SJY2 | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | Formyl_trans_N domain-containing protein. | 0.419 |
A0A1L9SC95 | A0A1L9SN20 | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. | Uncharacterized protein. | 0.877 |