STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cofCPhospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (207 aa)    
Predicted Functional Partners:
cofD
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
  
 0.981
cofG
FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
 
   
 0.872
cetZ
Cell division GTPase FtsZ; Involved in cell shape control; Belongs to the CetZ family.
 
     0.783
SEI53243.1
FO synthase subunit 2.
 
   
 0.748
SEI47140.1
Hypothetical protein.
  
     0.745
SEJ26629.1
ACT domain-containing protein.
  
     0.737
SEJ09165.1
Hypothetical protein.
  
     0.734
SEI99549.1
TIM-barrel protein, putative.
 
     0.719
SEI74920.1
Putative transcriptional regulator.
  
     0.718
SEI75521.1
Hypothetical protein; Belongs to the UPF0212 family.
  
     0.702
Your Current Organism:
Halohasta litchfieldiae
NCBI taxonomy Id: 1073996
Other names: CGMCC 1.12394, DSM 22187, H. litchfieldiae, Halobacteriaceae archaeon tADL, Halohasta litchfieldiae Mou et al. 2013, JCM 15066, halophilic archaeon True-ADL, strain tADL
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