SDM25616.1 protein (Catalinimonas alkaloidigena)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SDM25616.1

Glycosyl hydrolases family 16. (280 aa)

Predicted Functional Partners:

SDJ89811.1

0.644

SDK31928.1

0.621

SDM25576.1

0.526

SDJ97214.1

0.454

SDK23263.1

0.422

SDM17329.1

0.407

Your Current Organism:

Catalinimonas alkaloidigena

NCBI taxonomy Id: 1075417
Other names: Bacteroidetes bacterium CNU-914, C. alkaloidigena, Catalinimonas alkaloidigena Choi et al. 2013, DSM 25186, KCCM 90101, strain CNU-914

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDJ89811.1	SDM25616.1	SAMN05421823_101364	SAMN05421823_111237	Por secretion system C-terminal sorting domain-containing protein; Belongs to the glycosyl hydrolase 26 family.	Glycosyl hydrolases family 16.	0.644
SDJ97214.1	SDM25616.1	SAMN05421823_101555	SAMN05421823_111237	Polysaccharide deacetylase.	Glycosyl hydrolases family 16.	0.454
SDK23263.1	SDM25616.1	SAMN05421823_102203	SAMN05421823_111237	Beta-glucosidase.	Glycosyl hydrolases family 16.	0.422
SDK31928.1	SDM25616.1	SAMN05421823_102436	SAMN05421823_111237	Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.	Glycosyl hydrolases family 16.	0.621
SDM17329.1	SDM25616.1	SAMN05421823_1115	SAMN05421823_111237	Hexosaminidase.	Glycosyl hydrolases family 16.	0.407
SDM25576.1	SDM25616.1	SAMN05421823_111236	SAMN05421823_111237	Conserved repeat domain-containing protein/Por secretion system C-terminal sorting domain-containing protein.	Glycosyl hydrolases family 16.	0.526
SDM25616.1	SDJ89811.1	SAMN05421823_111237	SAMN05421823_101364	Glycosyl hydrolases family 16.	Por secretion system C-terminal sorting domain-containing protein; Belongs to the glycosyl hydrolase 26 family.	0.644
SDM25616.1	SDJ97214.1	SAMN05421823_111237	SAMN05421823_101555	Glycosyl hydrolases family 16.	Polysaccharide deacetylase.	0.454
SDM25616.1	SDK23263.1	SAMN05421823_111237	SAMN05421823_102203	Glycosyl hydrolases family 16.	Beta-glucosidase.	0.422
SDM25616.1	SDK31928.1	SAMN05421823_111237	SAMN05421823_102436	Glycosyl hydrolases family 16.	Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.	0.621
SDM25616.1	SDM17329.1	SAMN05421823_111237	SAMN05421823_1115	Glycosyl hydrolases family 16.	Hexosaminidase.	0.407
SDM25616.1	SDM25576.1	SAMN05421823_111237	SAMN05421823_111236	Glycosyl hydrolases family 16.	Conserved repeat domain-containing protein/Por secretion system C-terminal sorting domain-containing protein.	0.526

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.818

expected number of edges:

20

PPI enrichment p-value:

0.0113

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019470

4-hydroxyproline catabolic process

2 of 2

2.56

1.03

0.0133

GO:0046653

Tetrahydrofolate metabolic process

3 of 18

1.78

0.95

0.0133

GO:1901606

Alpha-amino acid catabolic process

3 of 28

1.59

0.9

0.0133

GO:0006575

Cellular modified amino acid metabolic process

5 of 102

1.25

0.87

0.0067

GO:0046416

D-amino acid metabolic process

2 of 6

2.08

0.87

0.0231

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008115

Sarcosine oxidase activity

3 of 9

2.08

1.58

0.00085

GO:0016645

Oxidoreductase activity, acting on the CH-NH group of donors

4 of 33

1.64

1.42

0.00074

GO:0016491

Oxidoreductase activity

9 of 515

0.8

0.69

0.00034

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1927

GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1, and Sarcosine oxidase, delta subunit family

4 of 24

1.78

1.79

0.00013

CL:1922

Mixed, incl. GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1, and NADH:flavin oxidoreductase / NADH oxidase family

5 of 50

1.56

1.63

0.00011

CL:1929

FAD dependent oxidoreductase central domain, and Sarcosine oxidase activity

3 of 18

1.78

1.3

0.0022

CL:1699

Mixed, incl. Carbon metabolism, and Oxidoreductase activity, acting on the CH-NH group of donors

7 of 181

1.15

0.00011

CL:5479

Mixed, incl. Alkylhydroperoxidase AhpD core, and EF-hand, calcium binding motif

2 of 6

2.08

0.92

0.0187

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00472

D-Arginine and D-ornithine metabolism

2 of 3

2.39

1.17

0.0071

map00330

Arginine and proline metabolism

3 of 57

1.28

0.73

0.0203

map01100

Metabolic pathways

11 of 1641

0.39

0.31

0.0071

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

10 of 1255

0.46

0.34

0.0135

GOCC:0005622

Intracellular

11 of 1613

0.39

0.3

0.0135

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF07992

Pyridine nucleotide-disulphide oxidoreductase

4 of 16

1.96

1.99

8.26e-05

PF13510

2Fe-2S iron-sulfur cluster binding domain

3 of 7

2.19

1.71

0.00052

PF04324

BFD-like [2Fe-2S] binding domain

2 of 2

2.56

1.27

0.0047

PF08669

Glycine cleavage T-protein C-terminal barrel domain

3 of 19

1.76

1.19

0.0038

PF01571

Aminomethyltransferase folate-binding domain

3 of 18

1.78

1.19

0.0038

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR041117

SoxA, A3 domain

5 of 5

2.56

4.02

1.96e-08

IPR041854

BFD-like [2Fe-2S]-binding domain superfamily

4 of 4

2.56

3.17

1.04e-06

IPR036188

FAD/NAD(P)-binding domain superfamily

7 of 80

1.5

2.15

3.98e-07

IPR042204

2Fe-2S iron-sulfur cluster binding domain, N-terminal

3 of 5

2.34

1.91

0.00025

IPR023753

FAD/NAD(P)-binding domain

4 of 24

1.78

1.7

0.00022

(more ...)

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