node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NCS6 | PCON_02318 | U4LKQ3 | U4LH76 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | 0.468 |
NCS6 | PCON_06048 | U4LKQ3 | U4KXD1 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | Similar to Uncharacterized protein C13D6.03c acc. no. Q10224. | 0.607 |
NCS6 | PCON_06177 | U4LKQ3 | U4KYG0 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | Similar to tRNA (Guanine(10)-N2)-methyltransferase acc. no. Q12463. | 0.441 |
NCS6 | PCON_06555 | U4LKQ3 | U4L3T4 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | Similar to Protein trm-112 acc. no. Q8X0S4. | 0.566 |
PCON_01793 | PCON_02318 | U4KTR8 | U4LH76 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | 0.996 |
PCON_01793 | PCON_06048 | U4KTR8 | U4KXD1 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | Similar to Uncharacterized protein C13D6.03c acc. no. Q10224. | 0.592 |
PCON_01793 | PCON_06177 | U4KTR8 | U4KYG0 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | Similar to tRNA (Guanine(10)-N2)-methyltransferase acc. no. Q12463. | 0.495 |
PCON_01793 | PCON_06430 | U4KTR8 | U4L3F0 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | 20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. | 0.999 |
PCON_01793 | PCON_06555 | U4KTR8 | U4L3T4 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | Similar to Protein trm-112 acc. no. Q8X0S4. | 0.767 |
PCON_01793 | PCON_11972 | U4KTR8 | U4LRE7 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | Similar to Uncharacterized protein C13G1.09 acc. no. O60071. | 0.999 |
PCON_01793 | PCON_13314 | U4KTR8 | U4L9G6 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | 40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. | 0.975 |
PCON_01793 | PCON_13315 | U4KTR8 | U4L8H1 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | Similar to Protein LTV1 acc. no. Q10191. | 0.999 |
PCON_01793 | PCON_13757 | U4KTR8 | U4LVX2 | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | 40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.882 |
PCON_02318 | NCS6 | U4LH76 | U4LKQ3 | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.468 |
PCON_02318 | PCON_01793 | U4LH76 | U4KTR8 | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956. | 0.996 |
PCON_02318 | PCON_06048 | U4LH76 | U4KXD1 | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | Similar to Uncharacterized protein C13D6.03c acc. no. Q10224. | 0.566 |
PCON_02318 | PCON_06177 | U4LH76 | U4KYG0 | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | Similar to tRNA (Guanine(10)-N2)-methyltransferase acc. no. Q12463. | 0.412 |
PCON_02318 | PCON_06430 | U4LH76 | U4L3F0 | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | 20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. | 0.998 |
PCON_02318 | PCON_06555 | U4LH76 | U4L3T4 | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | Similar to Protein trm-112 acc. no. Q8X0S4. | 0.597 |
PCON_02318 | PCON_11972 | U4LH76 | U4LRE7 | Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5. | Similar to Uncharacterized protein C13G1.09 acc. no. O60071. | 0.999 |