STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCON_06048Similar to Uncharacterized protein C13D6.03c acc. no. Q10224. (277 aa)    
Predicted Functional Partners:
PCON_06555
Similar to Protein trm-112 acc. no. Q8X0S4.
   
 0.958
PCON_06430
20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.
   
  0.731
NCS6
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
   
 
 0.607
PCON_06177
Similar to tRNA (Guanine(10)-N2)-methyltransferase acc. no. Q12463.
   
 
 0.595
PCON_01793
Similar to Ribosome biogenesis protein tsr1 homolog acc. no. O13956.
   
  0.592
PCON_11972
Similar to Uncharacterized protein C13G1.09 acc. no. O60071.
   
  0.585
PCON_02318
Similar to Pre-rRNA-processing protein PNO1 acc. no. Q1DQZ5.
   
  0.566
PCON_13315
Similar to Protein LTV1 acc. no. Q10191.
   
  0.556
PCON_13757
40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.
    
  0.539
PCON_13314
40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.
   
  0.537
Your Current Organism:
Pyronema omphalodes
NCBI taxonomy Id: 1076935
Other names: P. omphalodes CBS 100304, Pyronema confluens CBS 100304, Pyronema confluens CBS100304, Pyronema omphalodes CBS 100304, Pyronema omphalodes CBS100304
Server load: low (18%) [HD]