STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH; Belongs to the 6-phosphogluconate dehydrogenase family (468 aa)    
Predicted Functional Partners:
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
  
 
 0.957
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
  
 
 0.946
rpe
Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate
  
 0.944
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
  
 
 0.937
pgl
6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
    
 0.924
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
  
 
 0.855
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family
     
 0.767
hisI
annotation not available
     
 0.755
hisB
annotation not available
  
    0.729
dnaK
Chaperone protein DnaK; Acts as a chaperone
   
 
 0.715
Your Current Organism:
Buchnera aphidicola APS
NCBI taxonomy Id: 107806
Other names: B. aphidicola str. APS (Acyrthosiphon pisum), Buchnera aphidicola APS, Buchnera aphidicola str. APS, Buchnera aphidicola str. APS (Acyrthosiphon pisum), Buchnera aphidicola strain APS (Acyrthosiphon pisum), Buchnera sp. APS
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