Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysK | glyA | BUAP5A_065 | BUAP5A_284 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.519 |
| cysK | metE | BUAP5A_065 | BUAP5A_029 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.888 |
| cysK | metF | BUAP5A_065 | BUAP5A_045 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.465 |
| cysK | metK | BUAP5A_065 | BUAP5A_401 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.479 |
| cysK | thrA | BUAP5A_065 | BUAP5A_191 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.575 |
| glyA | cysK | BUAP5A_284 | BUAP5A_065 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.519 |
| glyA | ilvC | BUAP5A_284 | BUAP5A_591 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.461 |
| glyA | metE | BUAP5A_284 | BUAP5A_029 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.619 |
| glyA | metF | BUAP5A_284 | BUAP5A_045 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.960 |
| glyA | metG | BUAP5A_284 | BUAP5A_107 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.490 |
| glyA | metK | BUAP5A_284 | BUAP5A_401 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.826 |
| glyA | pheA | BUAP5A_284 | BUAP5A_385 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate. | 0.575 |
| glyA | thrA | BUAP5A_284 | BUAP5A_191 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.750 |
| hisB | ilvC | BUAP5A_100 | BUAP5A_591 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.589 |
| hisB | metE | BUAP5A_100 | BUAP5A_029 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.561 |
| hisB | metF | BUAP5A_100 | BUAP5A_045 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.491 |
| hisB | metG | BUAP5A_100 | BUAP5A_107 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.524 |
| hisB | metK | BUAP5A_100 | BUAP5A_401 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.548 |
| hisB | pheA | BUAP5A_100 | BUAP5A_385 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate. | 0.951 |
| hisB | thrA | BUAP5A_100 | BUAP5A_191 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.827 |
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