STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ytfNHypothetical protein. (970 aa)    
Predicted Functional Partners:
ftsB
Essential cell division protein FtsB (YgbQ); Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly extracellular; Belongs to the FtsB family.
  
     0.766
ompF
OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane.
  
     0.764
yhfC
YhfC MFS transporter.
  
     0.759
yciC
Predicted inner membrane protein (YciC).
  
     0.754
ftsL
Cell division protein; Essential cell division protein; Belongs to the FtsL family.
  
     0.746
holA
DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity).
  
     0.710
yeeX
Hypothetical protein; Belongs to the UPF0265 family.
  
     0.706
yheL
Hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
  
     0.635
ygfZ
Folate-binding protein (YgfZ); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.
  
     0.632
yaeT
YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
   
 0.606
Your Current Organism:
Buchnera aphidicola 5A
NCBI taxonomy Id: 563178
Other names: B. aphidicola str. 5A (Acyrthosiphon pisum), Buchnera aphidicola str. 5A (Acyrthosiphon pisum), Buchnera aphidicola strain 5A (Acyrthosiphon pisum)
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