STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hnsDNA-binding protein H-ns; A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome. A subset of genes are repressed by H-NS in association with other proteins (By similarity). (135 aa)    
Predicted Functional Partners:
ftsL
Cell division protein; Essential cell division protein; Belongs to the FtsL family.
  
     0.742
yciC
Predicted inner membrane protein (YciC).
 
     0.734
ompF
OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane.
  
    0.729
ftsB
Essential cell division protein FtsB (YgbQ); Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly extracellular; Belongs to the FtsB family.
  
     0.711
ppiD
Peptidyl-prolyl cis-trans isomerase D; PPIases accelerate the folding of proteins.
  
     0.661
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
   
    0.644
yfgM
Hypothetical protein.
  
    0.631
yhfC
YhfC MFS transporter.
  
     0.630
ytfN
Hypothetical protein.
  
     0.596
yeeX
Hypothetical protein; Belongs to the UPF0265 family.
  
    0.596
Your Current Organism:
Buchnera aphidicola 5A
NCBI taxonomy Id: 563178
Other names: B. aphidicola str. 5A (Acyrthosiphon pisum), Buchnera aphidicola str. 5A (Acyrthosiphon pisum), Buchnera aphidicola strain 5A (Acyrthosiphon pisum)
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