node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisB | hisI | BUAP5A_100 | BUAP5A_104 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.999 |
hisB | pheT | BUAP5A_100 | BUAP5A_128 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.424 |
hisB | thrA | BUAP5A_100 | BUAP5A_191 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.827 |
hisB | yeaZ | BUAP5A_100 | BUAP5A_317 | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity); Belongs to the KAE1 / TsaD family. TsaB subfamily. | 0.466 |
hisI | hisB | BUAP5A_104 | BUAP5A_100 | phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.999 |
hisI | pheT | BUAP5A_104 | BUAP5A_128 | phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.457 |
hisI | thrA | BUAP5A_104 | BUAP5A_191 | phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.972 |
hisI | yeaZ | BUAP5A_104 | BUAP5A_317 | phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity); Belongs to the KAE1 / TsaD family. TsaB subfamily. | 0.740 |
pheT | hisB | BUAP5A_128 | BUAP5A_100 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.424 |
pheT | hisI | BUAP5A_128 | BUAP5A_104 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.457 |
pheT | thrA | BUAP5A_128 | BUAP5A_191 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.764 |
pheT | yeaZ | BUAP5A_128 | BUAP5A_317 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity); Belongs to the KAE1 / TsaD family. TsaB subfamily. | 0.526 |
pheT | ygjD | BUAP5A_128 | BUAP5A_057 | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.753 |
rimN | thrA | BUAP5A_487 | BUAP5A_191 | dsRNA-binding protein, putative ribosome maturation factor (YrdC); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.437 |
rimN | yeaZ | BUAP5A_487 | BUAP5A_317 | dsRNA-binding protein, putative ribosome maturation factor (YrdC); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity); Belongs to the KAE1 / TsaD family. TsaB subfamily. | 0.635 |
rimN | ygjD | BUAP5A_487 | BUAP5A_057 | dsRNA-binding protein, putative ribosome maturation factor (YrdC); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.761 |
thrA | hisB | BUAP5A_191 | BUAP5A_100 | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Histidinol-phosphate phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.827 |
thrA | hisI | BUAP5A_191 | BUAP5A_104 | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | phosphoribosyl-AMP cyclohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.972 |
thrA | pheT | BUAP5A_191 | BUAP5A_128 | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.764 |
thrA | rimN | BUAP5A_191 | BUAP5A_487 | Bifunctional aspartokinase I/homeserine dehydrogenase I; Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | dsRNA-binding protein, putative ribosome maturation factor (YrdC); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.437 |