node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysG | ygfZ | BUAP5A_418 | BUAP5A_428 | Ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Folate-binding protein (YgfZ); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.722 |
holA | ompF | BUAP5A_438 | BUAP5A_352 | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane. | 0.683 |
holA | yb2331 | BUAP5A_438 | BUAP5A_096 | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | Hypothetical protein; Belongs to the UPF0115 family. | 0.400 |
holA | yciC | BUAP5A_438 | BUAP5A_271 | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | Predicted inner membrane protein (YciC). | 0.511 |
holA | ygfZ | BUAP5A_438 | BUAP5A_428 | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | Folate-binding protein (YgfZ); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.768 |
holA | yhfC | BUAP5A_438 | BUAP5A_528 | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | YhfC MFS transporter. | 0.563 |
holA | ytfN | BUAP5A_438 | BUAP5A_086 | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | Hypothetical protein. | 0.710 |
nfuA | yadR | BUAP5A_537 | BUAP5A_208 | Iron-sulfur cluster scaffold protein (YhgI); Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Essential respiratory protein A (YadR); Required for insertion of 4Fe-4S clusters for at least IspG. | 0.735 |
nfuA | ygfZ | BUAP5A_537 | BUAP5A_428 | Iron-sulfur cluster scaffold protein (YhgI); Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Folate-binding protein (YgfZ); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.695 |
ompF | holA | BUAP5A_352 | BUAP5A_438 | OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane. | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | 0.683 |
ompF | yciC | BUAP5A_352 | BUAP5A_271 | OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane. | Predicted inner membrane protein (YciC). | 0.766 |
ompF | ygfZ | BUAP5A_352 | BUAP5A_428 | OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane. | Folate-binding protein (YgfZ); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.614 |
ompF | yhfC | BUAP5A_352 | BUAP5A_528 | OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane. | YhfC MFS transporter. | 0.768 |
ompF | ytfN | BUAP5A_352 | BUAP5A_086 | OmpF-like porin; Forms pores that allow passive diffusion of small molecules across the membrane. | Hypothetical protein. | 0.764 |
yadR | nfuA | BUAP5A_208 | BUAP5A_537 | Essential respiratory protein A (YadR); Required for insertion of 4Fe-4S clusters for at least IspG. | Iron-sulfur cluster scaffold protein (YhgI); Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.735 |
yadR | ygfZ | BUAP5A_208 | BUAP5A_428 | Essential respiratory protein A (YadR); Required for insertion of 4Fe-4S clusters for at least IspG. | Folate-binding protein (YgfZ); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.632 |
yadR | yggX | BUAP5A_208 | BUAP5A_546 | Essential respiratory protein A (YadR); Required for insertion of 4Fe-4S clusters for at least IspG. | Protein that protects iron-sulfur proteins against oxidative damage (YggX); Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.590 |
yb2331 | holA | BUAP5A_096 | BUAP5A_438 | Hypothetical protein; Belongs to the UPF0115 family. | DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity). | 0.400 |
yb2331 | ygfZ | BUAP5A_096 | BUAP5A_428 | Hypothetical protein; Belongs to the UPF0115 family. | Folate-binding protein (YgfZ); Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.632 |
yb2331 | yhfC | BUAP5A_096 | BUAP5A_528 | Hypothetical protein; Belongs to the UPF0115 family. | YhfC MFS transporter. | 0.413 |