| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaN_1 | hda | BVIR_558 | BVIR_1078 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DnaA regulatory inactivator Hda. | 0.983 |
| dnaN_1 | recF_1 | BVIR_558 | BVIR_559 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.960 |
| dnaN_1 | recO | BVIR_558 | BVIR_815 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.578 |
| dnaN_1 | topA | BVIR_558 | BVIR_1660 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.657 |
| hda | dnaN_1 | BVIR_1078 | BVIR_558 | DnaA regulatory inactivator Hda. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.983 |
| hda | pgsA2 | BVIR_1078 | BVIR_1076 | DnaA regulatory inactivator Hda. | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase 2. | 0.629 |
| hda | ppk | BVIR_1078 | BVIR_1079 | DnaA regulatory inactivator Hda. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.557 |
| hda | recF_1 | BVIR_1078 | BVIR_559 | DnaA regulatory inactivator Hda. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.721 |
| hda | recO | BVIR_1078 | BVIR_815 | DnaA regulatory inactivator Hda. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.688 |
| hda | ribE | BVIR_1078 | BVIR_2187 | DnaA regulatory inactivator Hda. | Riboflavin synthase. | 0.564 |
| hda | rpmE | BVIR_1078 | BVIR_72 | DnaA regulatory inactivator Hda. | 50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.671 |
| hda | rpmJ | BVIR_1078 | BVIR_769 | DnaA regulatory inactivator Hda. | 50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. | 0.694 |
| hda | topA | BVIR_1078 | BVIR_1660 | DnaA regulatory inactivator Hda. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.590 |
| hda | yhhT_2 | BVIR_1078 | BVIR_1077 | DnaA regulatory inactivator Hda. | Pheromone autoinducer 2 transporter. | 0.933 |
| pgsA2 | hda | BVIR_1076 | BVIR_1078 | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase 2. | DnaA regulatory inactivator Hda. | 0.629 |
| pgsA2 | yhhT_2 | BVIR_1076 | BVIR_1077 | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase 2. | Pheromone autoinducer 2 transporter. | 0.624 |
| ppk | hda | BVIR_1079 | BVIR_1078 | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | DnaA regulatory inactivator Hda. | 0.557 |
| ppk | yhhT_2 | BVIR_1079 | BVIR_1077 | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | Pheromone autoinducer 2 transporter. | 0.510 |
| recF_1 | dnaN_1 | BVIR_559 | BVIR_558 | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.960 |
| recF_1 | hda | BVIR_559 | BVIR_1078 | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | DnaA regulatory inactivator Hda. | 0.721 |