| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_2197 | cbs_1 | BVIR_2197 | BVIR_363 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Putative cystathionine beta-synthase. | 0.900 |
| BVIR_2197 | cysE_1 | BVIR_2197 | BVIR_1349 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine acetyltransferase. | 0.801 |
| BVIR_2197 | glyA2 | BVIR_2197 | BVIR_2190 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| BVIR_2197 | ilvA_1 | BVIR_2197 | BVIR_2884 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-threonine dehydratase biosynthetic IlvA. | 0.901 |
| BVIR_2197 | serB_1 | BVIR_2197 | BVIR_3017 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphoserine phosphatase. | 0.903 |
| BVIR_2197 | tdcB | BVIR_2197 | BVIR_952 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-threonine dehydratase catabolic TdcB. | 0.901 |
| BVIR_2197 | trpA | BVIR_2197 | BVIR_3244 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
| BVIR_2197 | trpB_1 | BVIR_2197 | BVIR_1116 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| BVIR_2197 | trpB_2 | BVIR_2197 | BVIR_3245 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| cbs_1 | BVIR_2197 | BVIR_363 | BVIR_2197 | Putative cystathionine beta-synthase. | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| cbs_1 | cysE_1 | BVIR_363 | BVIR_1349 | Putative cystathionine beta-synthase. | Serine acetyltransferase. | 0.958 |
| cbs_1 | glyA2 | BVIR_363 | BVIR_2190 | Putative cystathionine beta-synthase. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.955 |
| cbs_1 | ilvA_1 | BVIR_363 | BVIR_2884 | Putative cystathionine beta-synthase. | L-threonine dehydratase biosynthetic IlvA. | 0.930 |
| cbs_1 | serB_1 | BVIR_363 | BVIR_3017 | Putative cystathionine beta-synthase. | Phosphoserine phosphatase. | 0.949 |
| cbs_1 | tdcB | BVIR_363 | BVIR_952 | Putative cystathionine beta-synthase. | L-threonine dehydratase catabolic TdcB. | 0.930 |
| cbs_1 | trpA | BVIR_363 | BVIR_3244 | Putative cystathionine beta-synthase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.922 |
| cbs_1 | trpB_1 | BVIR_363 | BVIR_1116 | Putative cystathionine beta-synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| cbs_1 | trpB_2 | BVIR_363 | BVIR_3245 | Putative cystathionine beta-synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.908 |
| cbs_1 | trpC | BVIR_363 | BVIR_1599 | Putative cystathionine beta-synthase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.414 |
| cysE_1 | BVIR_2197 | BVIR_1349 | BVIR_2197 | Serine acetyltransferase. | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.801 |