| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_1497 | nnr | BVIR_1497 | BVIR_1037 | Putative TrmH family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] | 0.599 |
| BVIR_1497 | rlmD | BVIR_1497 | BVIR_1958 | Putative TrmH family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.452 |
| BVIR_1497 | rpsA | BVIR_1497 | BVIR_2808 | Putative TrmH family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.591 |
| BVIR_1497 | trmB_1 | BVIR_1497 | BVIR_623 | Putative TrmH family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.541 |
| BVIR_1956 | rlmD | BVIR_1956 | BVIR_1958 | CorA-like Mg2+ transporter protein. | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.571 |
| BVIR_1956 | tlyA | BVIR_1956 | BVIR_1957 | CorA-like Mg2+ transporter protein. | 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA. | 0.559 |
| guaA_2 | rlmD | BVIR_227 | BVIR_1958 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.526 |
| guaA_2 | rpoC | BVIR_227 | BVIR_1367 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.870 |
| guaA_2 | rpsA | BVIR_227 | BVIR_2808 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.738 |
| guaA_2 | trmB_1 | BVIR_227 | BVIR_623 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.431 |
| nnr | BVIR_1497 | BVIR_1037 | BVIR_1497 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] | Putative TrmH family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.599 |
| nnr | rlmD | BVIR_1037 | BVIR_1958 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.488 |
| rlmD | BVIR_1497 | BVIR_1958 | BVIR_1497 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Putative TrmH family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.452 |
| rlmD | BVIR_1956 | BVIR_1958 | BVIR_1956 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | CorA-like Mg2+ transporter protein. | 0.571 |
| rlmD | guaA_2 | BVIR_1958 | BVIR_227 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.526 |
| rlmD | nnr | BVIR_1958 | BVIR_1037 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] | 0.488 |
| rlmD | rpoC | BVIR_1958 | BVIR_1367 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.457 |
| rlmD | rpsA | BVIR_1958 | BVIR_2808 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.481 |
| rlmD | rsmB_1 | BVIR_1958 | BVIR_3322 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.533 |
| rlmD | rsmB_2 | BVIR_1958 | BVIR_223 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.504 |