| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_118 | ligT | BVIR_118 | BVIR_20 | Possibl zinc metallo-peptidase. | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.404 |
| BVIR_1616 | ligT | BVIR_1616 | BVIR_20 | Rhomboid family protein. | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.424 |
| BVIR_17 | ligT | BVIR_17 | BVIR_20 | FtsX-like permease family protein. | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.555 |
| BVIR_17 | lolD_2 | BVIR_17 | BVIR_18 | FtsX-like permease family protein. | Putative ABC transporter ATP-binding protein. | 0.975 |
| BVIR_17 | tesA | BVIR_17 | BVIR_19 | FtsX-like permease family protein. | Acyl-CoA thioesterase I precursor. | 0.962 |
| BVIR_2501 | BVIR_37 | BVIR_2501 | BVIR_37 | Calcineurin-like phosphoesterase. | Hypothetical protein. | 0.457 |
| BVIR_2501 | ligT | BVIR_2501 | BVIR_20 | Calcineurin-like phosphoesterase. | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.494 |
| BVIR_37 | BVIR_2501 | BVIR_37 | BVIR_2501 | Hypothetical protein. | Calcineurin-like phosphoesterase. | 0.457 |
| BVIR_37 | ligT | BVIR_37 | BVIR_20 | Hypothetical protein. | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.411 |
| fes | ligT | BVIR_3129 | BVIR_20 | Enterochelin esterase. | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.441 |
| ispDF | ligT | BVIR_1921 | BVIR_20 | Bifunctional enzyme IspD/IspF; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.411 |
| ligT | BVIR_118 | BVIR_20 | BVIR_118 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Possibl zinc metallo-peptidase. | 0.404 |
| ligT | BVIR_1616 | BVIR_20 | BVIR_1616 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Rhomboid family protein. | 0.424 |
| ligT | BVIR_17 | BVIR_20 | BVIR_17 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | FtsX-like permease family protein. | 0.555 |
| ligT | BVIR_2501 | BVIR_20 | BVIR_2501 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Calcineurin-like phosphoesterase. | 0.494 |
| ligT | BVIR_37 | BVIR_20 | BVIR_37 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Hypothetical protein. | 0.411 |
| ligT | fes | BVIR_20 | BVIR_3129 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Enterochelin esterase. | 0.441 |
| ligT | ispDF | BVIR_20 | BVIR_1921 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Bifunctional enzyme IspD/IspF; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.411 |
| ligT | lolD_2 | BVIR_20 | BVIR_18 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Putative ABC transporter ATP-binding protein. | 0.557 |
| ligT | phhB | BVIR_20 | BVIR_21 | 2'-5'-RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Putative pterin-4-alpha-carbinolamine dehydratase. | 0.780 |