| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_218 | BVIR_219 | BVIR_218 | BVIR_219 | Hypothetical protein. | Putative metallophosphoesterase YhaO. | 0.960 |
| BVIR_218 | guaB | BVIR_218 | BVIR_221 | Hypothetical protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.470 |
| BVIR_218 | hsrA | BVIR_218 | BVIR_220 | Hypothetical protein. | Putative transport protein HsrA; Belongs to the major facilitator superfamily. | 0.773 |
| BVIR_219 | BVIR_218 | BVIR_219 | BVIR_218 | Putative metallophosphoesterase YhaO. | Hypothetical protein. | 0.960 |
| BVIR_219 | guaB | BVIR_219 | BVIR_221 | Putative metallophosphoesterase YhaO. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.568 |
| BVIR_219 | hsrA | BVIR_219 | BVIR_220 | Putative metallophosphoesterase YhaO. | Putative transport protein HsrA; Belongs to the major facilitator superfamily. | 0.773 |
| BVIR_219 | petB | BVIR_219 | BVIR_2484 | Putative metallophosphoesterase YhaO. | Cytochrome b/c1; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.709 |
| BVIR_219 | polA_1 | BVIR_219 | BVIR_2749 | Putative metallophosphoesterase YhaO. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.992 |
| BVIR_219 | rapA | BVIR_219 | BVIR_1196 | Putative metallophosphoesterase YhaO. | RNA polymerase-associated protein RapA. | 0.525 |
| BVIR_219 | recA | BVIR_219 | BVIR_1014 | Putative metallophosphoesterase YhaO. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.813 |
| BVIR_219 | recN_1 | BVIR_219 | BVIR_414 | Putative metallophosphoesterase YhaO. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.563 |
| BVIR_219 | topA | BVIR_219 | BVIR_1660 | Putative metallophosphoesterase YhaO. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.873 |
| BVIR_219 | uvrD_1 | BVIR_219 | BVIR_2724 | Putative metallophosphoesterase YhaO. | DNA helicase II. | 0.557 |
| guaB | BVIR_218 | BVIR_221 | BVIR_218 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Hypothetical protein. | 0.470 |
| guaB | BVIR_219 | BVIR_221 | BVIR_219 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Putative metallophosphoesterase YhaO. | 0.568 |
| guaB | hsrA | BVIR_221 | BVIR_220 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Putative transport protein HsrA; Belongs to the major facilitator superfamily. | 0.483 |
| guaB | polA_1 | BVIR_221 | BVIR_2749 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.585 |
| guaB | recA | BVIR_221 | BVIR_1014 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.487 |
| hsrA | BVIR_218 | BVIR_220 | BVIR_218 | Putative transport protein HsrA; Belongs to the major facilitator superfamily. | Hypothetical protein. | 0.773 |
| hsrA | BVIR_219 | BVIR_220 | BVIR_219 | Putative transport protein HsrA; Belongs to the major facilitator superfamily. | Putative metallophosphoesterase YhaO. | 0.773 |