| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_1012 | cusR_1 | BVIR_1012 | BVIR_2332 | Blue-light-activated protein. | Transcriptional activator protein CzcR. | 0.826 |
| BVIR_1012 | cusS | BVIR_1012 | BVIR_2331 | Blue-light-activated protein. | Sensor kinase CusS. | 0.483 |
| BVIR_1012 | glnE | BVIR_1012 | BVIR_2330 | Blue-light-activated protein. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.409 |
| BVIR_1012 | gltB_1 | BVIR_1012 | BVIR_2568 | Blue-light-activated protein. | Ferredoxin-dependent glutamate synthase 1. | 0.563 |
| BVIR_1012 | nadE_1 | BVIR_1012 | BVIR_785 | Blue-light-activated protein. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.585 |
| BVIR_1012 | pleC_1 | BVIR_1012 | BVIR_631 | Blue-light-activated protein. | Non-motile and phage-resistance protein. | 0.772 |
| bcp | glnE | BVIR_1124 | BVIR_2330 | Putative peroxiredoxin bcp. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.669 |
| cusR_1 | BVIR_1012 | BVIR_2332 | BVIR_1012 | Transcriptional activator protein CzcR. | Blue-light-activated protein. | 0.826 |
| cusR_1 | cusS | BVIR_2332 | BVIR_2331 | Transcriptional activator protein CzcR. | Sensor kinase CusS. | 0.978 |
| cusR_1 | glnE | BVIR_2332 | BVIR_2330 | Transcriptional activator protein CzcR. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.822 |
| cusR_1 | mucD_3 | BVIR_2332 | BVIR_2333 | Transcriptional activator protein CzcR. | Putative periplasmic serine endoprotease DegP-like precursor; Belongs to the peptidase S1C family. | 0.555 |
| cusR_1 | pleC_1 | BVIR_2332 | BVIR_631 | Transcriptional activator protein CzcR. | Non-motile and phage-resistance protein. | 0.583 |
| cusS | BVIR_1012 | BVIR_2331 | BVIR_1012 | Sensor kinase CusS. | Blue-light-activated protein. | 0.483 |
| cusS | cusR_1 | BVIR_2331 | BVIR_2332 | Sensor kinase CusS. | Transcriptional activator protein CzcR. | 0.978 |
| cusS | glnE | BVIR_2331 | BVIR_2330 | Sensor kinase CusS. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.822 |
| cusS | mucD_3 | BVIR_2331 | BVIR_2333 | Sensor kinase CusS. | Putative periplasmic serine endoprotease DegP-like precursor; Belongs to the peptidase S1C family. | 0.561 |
| glnA | glnD | BVIR_1035 | BVIR_2826 | Glutamine synthetase 1. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.412 |
| glnA | glnE | BVIR_1035 | BVIR_2330 | Glutamine synthetase 1. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.693 |
| glnA | gltB_1 | BVIR_1035 | BVIR_2568 | Glutamine synthetase 1. | Ferredoxin-dependent glutamate synthase 1. | 0.983 |
| glnA | nadE_1 | BVIR_1035 | BVIR_785 | Glutamine synthetase 1. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.535 |
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