| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_702 | folP_1 | BVIR_702 | BVIR_2635 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.646 |
| fgs | folB | BVIR_3242 | BVIR_2636 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.712 |
| fgs | folE_1 | BVIR_3242 | BVIR_1779 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase 1. | 0.712 |
| fgs | folP_1 | BVIR_3242 | BVIR_2635 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
| fgs | sulD | BVIR_3242 | BVIR_2637 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Bifunctional folate synthesis protein. | 0.945 |
| fgs | trpE_2 | BVIR_3242 | BVIR_2862 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Anthranilate synthase component 1. | 0.539 |
| folB | fgs | BVIR_2636 | BVIR_3242 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.712 |
| folB | folE_1 | BVIR_2636 | BVIR_1779 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase 1. | 0.965 |
| folB | folP_1 | BVIR_2636 | BVIR_2635 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| folB | sulD | BVIR_2636 | BVIR_2637 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional folate synthesis protein. | 0.999 |
| folB | trpE_2 | BVIR_2636 | BVIR_2862 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Anthranilate synthase component 1. | 0.539 |
| folE_1 | fgs | BVIR_1779 | BVIR_3242 | GTP cyclohydrolase 1. | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.712 |
| folE_1 | folB | BVIR_1779 | BVIR_2636 | GTP cyclohydrolase 1. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.965 |
| folE_1 | folP_1 | BVIR_1779 | BVIR_2635 | GTP cyclohydrolase 1. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.986 |
| folE_1 | guaB | BVIR_1779 | BVIR_221 | GTP cyclohydrolase 1. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.510 |
| folE_1 | sulD | BVIR_1779 | BVIR_2637 | GTP cyclohydrolase 1. | Bifunctional folate synthesis protein. | 0.997 |
| folE_1 | trpE_2 | BVIR_1779 | BVIR_2862 | GTP cyclohydrolase 1. | Anthranilate synthase component 1. | 0.568 |
| folP_1 | BVIR_702 | BVIR_2635 | BVIR_702 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.646 |
| folP_1 | fgs | BVIR_2635 | BVIR_3242 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.997 |
| folP_1 | folB | BVIR_2635 | BVIR_2636 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |