| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroE | entC_1 | BVIR_3285 | BVIR_918 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Salicylate biosynthesis isochorismate synthase. | 0.528 |
| aroE | pabA | BVIR_3285 | BVIR_1601 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate synthase component 2. | 0.676 |
| aroE | trpA | BVIR_3285 | BVIR_3244 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.623 |
| aroE | trpB_2 | BVIR_3285 | BVIR_3245 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.555 |
| aroE | trpC | BVIR_3285 | BVIR_1599 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.622 |
| aroE | trpD2 | BVIR_3285 | BVIR_1600 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.555 |
| aroE | trpE_1 | BVIR_3285 | BVIR_1603 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.593 |
| aroE | trpE_2 | BVIR_3285 | BVIR_2862 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate synthase component 1. | 0.647 |
| aroE | trpF | BVIR_3285 | BVIR_3246 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.563 |
| entC_1 | aroE | BVIR_918 | BVIR_3285 | Salicylate biosynthesis isochorismate synthase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.528 |
| entC_1 | pabA | BVIR_918 | BVIR_1601 | Salicylate biosynthesis isochorismate synthase. | Anthranilate synthase component 2. | 0.772 |
| entC_1 | trpA | BVIR_918 | BVIR_3244 | Salicylate biosynthesis isochorismate synthase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.712 |
| entC_1 | trpB_2 | BVIR_918 | BVIR_3245 | Salicylate biosynthesis isochorismate synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.598 |
| entC_1 | trpC | BVIR_918 | BVIR_1599 | Salicylate biosynthesis isochorismate synthase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.757 |
| entC_1 | trpD2 | BVIR_918 | BVIR_1600 | Salicylate biosynthesis isochorismate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.753 |
| entC_1 | trpE_2 | BVIR_918 | BVIR_2862 | Salicylate biosynthesis isochorismate synthase. | Anthranilate synthase component 1. | 0.472 |
| entC_1 | trpF | BVIR_918 | BVIR_3246 | Salicylate biosynthesis isochorismate synthase. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.702 |
| hisF | trpA | BVIR_3271 | BVIR_3244 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.553 |
| hisF | trpB_2 | BVIR_3271 | BVIR_3245 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.553 |
| hisF | trpC | BVIR_3271 | BVIR_1599 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.560 |