STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemA_15-aminolevulinate synthase. (409 aa)    
Predicted Functional Partners:
glyA2
Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.942
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
    
 0.939
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
  
 0.932
fabD
Malonyl CoA-acyl carrier protein transacylase.
 
 
 0.930
gcvPB
Putative glycine dehydrogenase (decarboxylating) subunit 2.
 
 
 0.929
gcvPA
Putative glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
  
 
 0.918
hemL_1
Beta-phenylalanine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.914
soxB
Sarcosine oxidase subunit beta.
  
 
 0.907
cobD-2
Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
     
 0.808
cobD
Threonine-phosphate decarboxylase.
     
  0.800
Your Current Organism:
Blastochloris viridis
NCBI taxonomy Id: 1079
Other names: ATCC 19567, B. viridis, CCUG 30818, CCUG 7830, DSM 133, LMG 4321, LMG:4321, NBRC 102659, Rhodopseudomonas viridis, strain G. Drews F
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