| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_765 | BVIR_766 | BVIR_765 | BVIR_766 | Ribonuclease I; Belongs to the RNase T2 family. | Hypothetical protein. | 0.857 |
| BVIR_765 | ldc_2 | BVIR_765 | BVIR_767 | Ribonuclease I; Belongs to the RNase T2 family. | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.494 |
| BVIR_766 | BVIR_765 | BVIR_766 | BVIR_765 | Hypothetical protein. | Ribonuclease I; Belongs to the RNase T2 family. | 0.857 |
| BVIR_766 | ldc_2 | BVIR_766 | BVIR_767 | Hypothetical protein. | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.494 |
| guaA_2 | guaB | BVIR_227 | BVIR_221 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA_2 | ldc_1 | BVIR_227 | BVIR_714 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.607 |
| guaA_2 | ldc_2 | BVIR_227 | BVIR_767 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.607 |
| guaA_2 | mosA | BVIR_227 | BVIR_2259 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.485 |
| guaA_2 | pheT | BVIR_227 | BVIR_3095 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.902 |
| guaA_2 | ribBA_1 | BVIR_227 | BVIR_1959 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.682 |
| guaA_2 | ribD | BVIR_227 | BVIR_2188 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.607 |
| guaB | guaA_2 | BVIR_221 | BVIR_227 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | ldc_1 | BVIR_221 | BVIR_714 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.402 |
| guaB | ldc_2 | BVIR_221 | BVIR_767 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.402 |
| guaB | pheT | BVIR_221 | BVIR_3095 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.776 |
| guaB | ribBA_1 | BVIR_221 | BVIR_1959 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.922 |
| guaB | ribD | BVIR_221 | BVIR_2188 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.636 |
| ldc_1 | guaA_2 | BVIR_714 | BVIR_227 | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.607 |
| ldc_1 | guaB | BVIR_714 | BVIR_221 | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.402 |
| ldc_1 | ldc_2 | BVIR_714 | BVIR_767 | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Lysine/ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.924 |