| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BVIR_2657 | BVIR_77 | BVIR_2657 | BVIR_77 | Succinate dehydrogenase/Fumarate reductase transmembrane subunit. | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.529 |
| BVIR_77 | BVIR_2657 | BVIR_77 | BVIR_2657 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Succinate dehydrogenase/Fumarate reductase transmembrane subunit. | 0.529 |
| BVIR_77 | BVIR_78 | BVIR_77 | BVIR_78 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Hypothetical protein. | 0.709 |
| BVIR_77 | BVIR_79 | BVIR_77 | BVIR_79 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.540 |
| BVIR_77 | dnaN_1 | BVIR_77 | BVIR_558 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.725 |
| BVIR_77 | grxC | BVIR_77 | BVIR_294 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Glutaredoxin-3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.528 |
| BVIR_77 | nrdE | BVIR_77 | BVIR_1098 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.958 |
| BVIR_77 | qmcA | BVIR_77 | BVIR_2577 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Modulator of FtsH protease HflC. | 0.534 |
| BVIR_77 | secB | BVIR_77 | BVIR_3282 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.625 |
| BVIR_77 | thyA_1 | BVIR_77 | BVIR_3053 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.574 |
| BVIR_77 | yrrK | BVIR_77 | BVIR_1653 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.774 |
| BVIR_78 | BVIR_77 | BVIR_78 | BVIR_77 | Hypothetical protein. | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.709 |
| BVIR_78 | BVIR_79 | BVIR_78 | BVIR_79 | Hypothetical protein. | Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.613 |
| BVIR_79 | BVIR_77 | BVIR_79 | BVIR_77 | Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.540 |
| BVIR_79 | BVIR_78 | BVIR_79 | BVIR_78 | Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | Hypothetical protein. | 0.613 |
| dnaN_1 | BVIR_77 | BVIR_558 | BVIR_77 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.725 |
| dnaN_1 | nrdE | BVIR_558 | BVIR_1098 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.773 |
| dnaN_1 | thyA_1 | BVIR_558 | BVIR_3053 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.785 |
| grxC | BVIR_77 | BVIR_294 | BVIR_77 | Glutaredoxin-3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.528 |
| grxC | nrdE | BVIR_294 | BVIR_1098 | Glutaredoxin-3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.944 |