| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dhbC | menB | BVIR_3122 | BVIR_915 | Isochorismate synthase DhbC. | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.406 |
| dhbC | menD | BVIR_3122 | BVIR_917 | Isochorismate synthase DhbC. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.972 |
| dhbC | ykfB | BVIR_3122 | BVIR_914 | Isochorismate synthase DhbC. | L-Ala-D/L-Glu epimerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.407 |
| dnaC | ykfB | BVIR_667 | BVIR_914 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | L-Ala-D/L-Glu epimerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.439 |
| entC_1 | menA | BVIR_918 | BVIR_563 | Salicylate biosynthesis isochorismate synthase. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.465 |
| entC_1 | menB | BVIR_918 | BVIR_915 | Salicylate biosynthesis isochorismate synthase. | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.923 |
| entC_1 | menD | BVIR_918 | BVIR_917 | Salicylate biosynthesis isochorismate synthase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.967 |
| entC_1 | menE_2 | BVIR_918 | BVIR_913 | Salicylate biosynthesis isochorismate synthase. | Long-chain-fatty-acid--CoA ligase. | 0.597 |
| entC_1 | menH | BVIR_918 | BVIR_916 | Salicylate biosynthesis isochorismate synthase. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase. | 0.904 |
| entC_1 | ykfB | BVIR_918 | BVIR_914 | Salicylate biosynthesis isochorismate synthase. | L-Ala-D/L-Glu epimerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.659 |
| menA | entC_1 | BVIR_563 | BVIR_918 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Salicylate biosynthesis isochorismate synthase. | 0.465 |
| menA | menB | BVIR_563 | BVIR_915 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.853 |
| menA | menD | BVIR_563 | BVIR_917 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.878 |
| menA | menH | BVIR_563 | BVIR_916 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase. | 0.741 |
| menA | ykfB | BVIR_563 | BVIR_914 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | L-Ala-D/L-Glu epimerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.586 |
| menB | dhbC | BVIR_915 | BVIR_3122 | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | Isochorismate synthase DhbC. | 0.406 |
| menB | entC_1 | BVIR_915 | BVIR_918 | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | Salicylate biosynthesis isochorismate synthase. | 0.923 |
| menB | menA | BVIR_915 | BVIR_563 | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.853 |
| menB | menD | BVIR_915 | BVIR_917 | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.979 |
| menB | menE_2 | BVIR_915 | BVIR_913 | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | Long-chain-fatty-acid--CoA ligase. | 0.979 |