SFP30224.1 protein (Pseudarcicella hirudinis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SFP30224.1

Carbohydrate family 9 binding domain-like. (363 aa)

Predicted Functional Partners:

SFP30203.1

0.994

SFP30246.1

0.518

SFP76022.1

0.454

SFP81420.1

0.446

SFP81398.1

0.421

Your Current Organism:

Pseudarcicella hirudinis

NCBI taxonomy Id: 1079859
Other names: Arcicella sp. E92, CCM 7988, LMG 26720, LMG:26720, P. hirudinis, Pseudarcicella hirudinis Kampfer et al. 2012, strain E92

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFP30203.1	SFP30224.1	SAMN04515674_102333	SAMN04515674_102334	Glycosyl hydrolase-like 10.	Carbohydrate family 9 binding domain-like.	0.994
SFP30203.1	SFP30246.1	SAMN04515674_102333	SAMN04515674_102335	Glycosyl hydrolase-like 10.	DNA-binding transcriptional regulator, LacI/PurR family.	0.518
SFP30203.1	SFP81398.1	SAMN04515674_102333	SAMN04515674_10610	Glycosyl hydrolase-like 10.	Starch-binding associating with outer membrane.	0.471
SFP30224.1	SFP30203.1	SAMN04515674_102334	SAMN04515674_102333	Carbohydrate family 9 binding domain-like.	Glycosyl hydrolase-like 10.	0.994
SFP30224.1	SFP30246.1	SAMN04515674_102334	SAMN04515674_102335	Carbohydrate family 9 binding domain-like.	DNA-binding transcriptional regulator, LacI/PurR family.	0.518
SFP30224.1	SFP76022.1	SAMN04515674_102334	SAMN04515674_105288	Carbohydrate family 9 binding domain-like.	Hypothetical protein.	0.454
SFP30224.1	SFP81398.1	SAMN04515674_102334	SAMN04515674_10610	Carbohydrate family 9 binding domain-like.	Starch-binding associating with outer membrane.	0.421
SFP30224.1	SFP81420.1	SAMN04515674_102334	SAMN04515674_10611	Carbohydrate family 9 binding domain-like.	TonB-linked outer membrane protein, SusC/RagA family.	0.446
SFP30246.1	SFP30203.1	SAMN04515674_102335	SAMN04515674_102333	DNA-binding transcriptional regulator, LacI/PurR family.	Glycosyl hydrolase-like 10.	0.518
SFP30246.1	SFP30224.1	SAMN04515674_102335	SAMN04515674_102334	DNA-binding transcriptional regulator, LacI/PurR family.	Carbohydrate family 9 binding domain-like.	0.518
SFP76022.1	SFP30224.1	SAMN04515674_105288	SAMN04515674_102334	Hypothetical protein.	Carbohydrate family 9 binding domain-like.	0.454
SFP81398.1	SFP30203.1	SAMN04515674_10610	SAMN04515674_102333	Starch-binding associating with outer membrane.	Glycosyl hydrolase-like 10.	0.471
SFP81398.1	SFP30224.1	SAMN04515674_10610	SAMN04515674_102334	Starch-binding associating with outer membrane.	Carbohydrate family 9 binding domain-like.	0.421
SFP81398.1	SFP81420.1	SAMN04515674_10610	SAMN04515674_10611	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.931
SFP81420.1	SFP30224.1	SAMN04515674_10611	SAMN04515674_102334	TonB-linked outer membrane protein, SusC/RagA family.	Carbohydrate family 9 binding domain-like.	0.446
SFP81420.1	SFP81398.1	SAMN04515674_10611	SAMN04515674_10610	TonB-linked outer membrane protein, SusC/RagA family.	Starch-binding associating with outer membrane.	0.931

Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.884

expected number of edges:

13

PPI enrichment p-value:

0.035

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 114

1.48

3.0

1.12e-13

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 53

1.77

4.37

1.47e-14

GO:0019843

rRNA binding

4 of 42

1.47

1.16

0.0020

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 60

1.72

4.16

8.83e-15

GO:0015935

Small ribosomal subunit

2 of 8

1.89

1.08

0.0078

GO:0005622

Intracellular anatomical structure

11 of 1255

0.44

0.38

0.00035

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:901

Structural constituent of ribosome

10 of 57

1.74

4.17

3.15e-14

CL:980

Structural constituent of ribosome

4 of 10

2.1

2.74

2.34e-06

CL:902

rRNA-binding, and RNA polymerase

6 of 38

1.69

2.72

6.37e-08

CL:903

rRNA-binding, and Protein transport by the Sec complex

5 of 31

1.7

2.33

1.84e-06

CL:905

rRNA-binding

3 of 26

1.56

1.14

0.0032

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 58

1.73

4.26

5.36e-15

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

8 of 52

1.68

3.25

2.20e-10

GOCC:0043232

Intracellular non-membrane-bounded organelle

9 of 147

1.28

1.92

4.29e-09

GOCC:0022626

Cytosolic ribosome

3 of 22

1.63

1.22

0.0024

GOCC:0043229

Intracellular organelle

10 of 324

0.98

1.17

4.30e-08

GOCC:0044391

Ribosomal subunit

3 of 27

1.54

1.11

0.0036

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 62

1.7

4.05

1.91e-14

KW-0699

rRNA-binding

4 of 39

1.51

1.39

0.00046

KW-0820

tRNA-binding

2 of 12

1.72

0.74

0.0352

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