STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP74078.1propionyl-CoA carboxylase beta chain. (518 aa)    
Predicted Functional Partners:
SFP74847.1
propionyl-CoA carboxylase alpha chain; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.998
SFP94231.1
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.998
SFQ48771.1
Biotin-requiring enzyme.
 
 0.997
SFP31746.1
Pyruvate carboxylase.
 
 0.965
SFP64039.1
methylmalonyl-CoA epimerase.
 
 
  0.962
SFQ10030.1
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.
  
 
 0.958
SFQ49632.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
 
 
 0.929
SFQ28683.1
acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.903
SFQ37049.1
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.899
SFQ28457.1
3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.884
Your Current Organism:
Pseudarcicella hirudinis
NCBI taxonomy Id: 1079859
Other names: Arcicella sp. E92, CCM 7988, LMG 26720, LMG:26720, P. hirudinis, Pseudarcicella hirudinis Kampfer et al. 2012, strain E92
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