STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFQ37179.1Malate synthase; Belongs to the malate synthase family. (544 aa)    
Predicted Functional Partners:
SFQ37199.1
Isocitrate lyase.
 
 0.999
SFP63724.1
Allosteric NADP-dependent malic enzyme.
  
 
 0.976
SFP05991.1
2-Methylisocitrate lyase, PEP mutase family.
   
 
 0.905
SFP63834.1
Citrate synthase; Belongs to the citrate synthase family.
   
 0.904
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.889
SFQ37049.1
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.887
SFP70307.1
FAD/FMN-containing dehydrogenase.
  
 
 0.839
SFQ44735.1
FAD/FMN-containing dehydrogenase.
  
 
 0.839
SFP10552.1
acetoacetyl-CoA synthetase.
   
 0.782
SFQ10030.1
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.
   
 
 0.780
Your Current Organism:
Pseudarcicella hirudinis
NCBI taxonomy Id: 1079859
Other names: Arcicella sp. E92, CCM 7988, LMG 26720, LMG:26720, P. hirudinis, Pseudarcicella hirudinis Kampfer et al. 2012, strain E92
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