node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS53880.1 | SIS65095.1 | SAMN05421774_10199 | SAMN05421774_101681 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.730 |
SIS53880.1 | cobD | SAMN05421774_10199 | SAMN05421774_10777 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.650 |
SIS53880.1 | cobQ | SAMN05421774_10199 | SAMN05421774_102536 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.677 |
SIS53880.1 | cobS | SAMN05421774_10199 | SAMN05421774_105135 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.634 |
SIS53880.1 | cobT | SAMN05421774_10199 | SAMN05421774_105136 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.614 |
SIS53880.1 | hemC | SAMN05421774_10199 | SAMN05421774_101469 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
SIS55982.1 | SIS65095.1 | SAMN05421774_101193 | SAMN05421774_101681 | Iron complex transport system ATP-binding protein. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.582 |
SIS55982.1 | SIS80161.1 | SAMN05421774_101193 | SAMN05421774_102355 | Iron complex transport system ATP-binding protein. | ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.602 |
SIS55982.1 | cobD | SAMN05421774_101193 | SAMN05421774_10777 | Iron complex transport system ATP-binding protein. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.605 |
SIS55982.1 | cobQ | SAMN05421774_101193 | SAMN05421774_102536 | Iron complex transport system ATP-binding protein. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.595 |
SIS65095.1 | SIS53880.1 | SAMN05421774_101681 | SAMN05421774_10199 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.730 |
SIS65095.1 | SIS55982.1 | SAMN05421774_101681 | SAMN05421774_101193 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Iron complex transport system ATP-binding protein. | 0.582 |
SIS65095.1 | SIS80161.1 | SAMN05421774_101681 | SAMN05421774_102355 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.945 |
SIS65095.1 | cobD | SAMN05421774_101681 | SAMN05421774_10777 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.994 |
SIS65095.1 | cobQ | SAMN05421774_101681 | SAMN05421774_102536 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.986 |
SIS65095.1 | cobS | SAMN05421774_101681 | SAMN05421774_105135 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.987 |
SIS65095.1 | cobT | SAMN05421774_101681 | SAMN05421774_105136 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.992 |
SIS65095.1 | hemC | SAMN05421774_101681 | SAMN05421774_101469 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.496 |
SIS65095.1 | hisC | SAMN05421774_101681 | SAMN05421774_104134 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.500 |
SIS65095.1 | hisC-2 | SAMN05421774_101681 | SAMN05421774_10725 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.500 |