STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribB-2GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (374 aa)    
Predicted Functional Partners:
SIS57158.1
Riboflavin synthase alpha chain.
 0.999
SIS67846.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.999
SIS62094.1
Flagellar motor switch protein FliG.
    
 
 0.956
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
  
 0.945
SIS82904.1
Two-component system, chemotaxis family, response regulator CheY.
  
 0.941
SIS82887.1
PAS domain S-box-containing protein.
  
 0.938
SIS82920.1
CheY chemotaxis protein or a CheY-like REC (receiver) domain.
  
 0.938
SIS82936.1
PAS domain S-box-containing protein.
  
 0.938
SIT17901.1
PAS domain S-box-containing protein.
  
 0.938
Your Current Organism:
Gemmobacter megaterium
NCBI taxonomy Id: 1086013
Other names: CGMCC 1.11024, Catellibacterium sp. CF17, DSM 26375, G. megaterium, Gemmobacter megaterium Liu et al. 2014, JCM 18498, strain CF17
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