STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobNCobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (1092 aa)    
Predicted Functional Partners:
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.985
cobW
Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.982
cobH
Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.978
AIT81405.1
precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.973
AIT81402.1
Catalyzes the formation of precorrin-3 from precorrin-2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.970
AIT81400.1
Cobalamin biosynthesis protein CobG; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
   
 0.967
AIT81403.1
Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.964
AIT78912.1
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.957
AIT80268.1
cob(I)yrinic acid a c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.925
cobT
Cobalt chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.918
Your Current Organism:
Novosphingobium pentaromativorans
NCBI taxonomy Id: 1088721
Other names: N. pentaromativorans US6-1, Novosphingobium pentaromativorans US6-1, Novosphingobium pentaromativorans str. US6-1, Novosphingobium pentaromativorans strain US6-1, Novosphingobium sp. US6-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.