STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoD2DNA-directed RNA polymerase sigma 70 subunit RpoD. (129 aa)    
Predicted Functional Partners:
AFV11881.1
RNA polymerase sigma factor, sigma-70 family.
 
     0.959
sigG1
Sporulation-specific RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.743
spoIIAB
spoIIAB: anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.735
sigG2
Sporulation sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
     0.729
fliN
Flagellar motor switch protein FliN.
  
  
 0.716
spoVAD
Stage V sporulation protein AD.
 
    0.711
spoVAC
Stage V sporulation protein AC.
 
     0.706
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.702
spoIIE
Stage II sporulation protein E.
  
  
 0.696
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.690
Your Current Organism:
Thermacetogenium phaeum
NCBI taxonomy Id: 1089553
Other names: Clostridiaceae str. PB, T. phaeum DSM 12270, Thermacetogenium phaeum DSM 12270, Thermacetogenium phaeum PB, Thermacetogenium phaeum str. DSM 12270, Thermacetogenium phaeum strain DSM 12270
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